Eighteen-year-old American Natalee Holloway disappeared on May 30, 2005, while on a high school graduation trip to Aruba. Joran van der Sloot was the prime suspect but was never charged in her case. She was declared legally dead in 2012.
On February 9, 2004, 21-year-old University of Massachusetts student Maura Murray crashed her car on Route 112 in Haverhill, New Hampshire, and vanished. Despite massive searches, she has never been found.
Three-year-old Madeleine McCann disappeared from her family's holiday apartment in Praia da Luz, Portugal, on May 3, 2007. She has never been found. German suspect Christian Brückner was identified in 2020 but has not been charged.